Galliprant for Dogs: Osteoarthritis Pain Relief

Reviewed by Catherine Barnette, DVM on 04/30/2024. Published on 04/10/2023

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Medication details

Medication type: NSAID
Form: Tablet
Prescription required? Yes
FDA approved? Yes
Brand names: Galliprant
Common names: Grapiprant
Available dosages: 20mg, 60mg, 100mg
Expiration range: Refer to package label for specific expiration date

Dogs with arthritis experience pain and inflammation within their joints, which can cause discomfort and trouble getting around. If your dog is experiencing arthritis pain, a veterinarian may prescribe a medication called Galliprant to provide some relief. While there are many options available to treat pain in dogs, Galliprant is an effective medication that is well-tolerated. Let’s learn more about Galliprant and why your dog’s veterinarian may recommend it.

What Is Galliprant for Dogs?

Galliprant is a type of non-steroidal anti-inflammatory drug (NSAID) prescribed by veterinarians to reduce pain and inflammation in dogs living with arthritis. It is manufactured by Elanco and was approved by the FDA for use in dogs in March 2016. It is a flavored, chewable tablet given by mouth once daily with less risk for side effects than other types of NSAIDs. Pet parents can get Galliprant from their dog’s primary care veterinarian, and it is readily available throughout the United States. This medication is also available in a generic form called grapiprant.

What Does Galliprant for Dogs Look Like?

Galliprant is an oval-shaped, light brown tablet that is imprinted with the letter “G.” The 20mg and 60mg tablets also have a score line where the pills can be split for easy dosing.

What Is Galliprant Used For in Dogs?

X-ray of degenerative joint disease in dog

Veterinarians prescribe Galliprant to reduce pain and inflammation in dogs with arthritis, which is a common condition that develops as pets age. Over time, the cartilage that cushions the joints begins to break down, and the bones within the joint start to rub against one another. As a result of this joint damage, the body begins producing substances called prostaglandins. The production of prostaglandins results in swelling and inflammation and is very painful for dogs. In order to alleviate this discomfort, veterinarians prescribe pain medications, such as Galliprant. This NSAID specifically targets the source of pain and inflammation by preventing prostaglandins from interacting with receptors that they use to function. As a result, pain and inflammation is reduced and dogs feel better.

How Does Galliprant Work?

NSAIDs are a type of medication used to reduce pain, inflammation, and fevers in dogs. Traditional NSAIDs, such as meloxicam, carprofen, and deracoxib, work by inhibiting an enzyme called cyclooxygenase, which is responsible for producing prostaglandins. These prostaglandins increase pain and inflammation within the body. Therefore, by inhibiting this enzyme, pain and inflammation is reduced. However, traditional NSAIDs can also have negative effects on the kidneys, liver, platelets, stomach, and intestines.

Galliprant is unique because it is considered a non-cyclooxygenase inhibiting NSAID. While this medication does not prevent the production of prostaglandins, it effectively blocks prostaglandins from interacting with specific receptors. This results in arthritic dogs experiencing less pain and inflammation. Due to the way this medication works, it also has less risk for negative effects on the liver, kidneys, and gastrointestinal tract compared to traditional NSAIDs [1].

How to Give Galliprant to Dogs

Woman holding out tablet in front of dog

Galliprant is given orally to dogs once daily. The tablets are pork-flavored, so the majority of dogs will eagerly take them. However, if your dog won’t readily take the medication, you can disguise it in wet food, a pill pocket, or a piece of cheese. If your dog still won’t take Galliprant using these tips, you can ask your pet’s veterinarian for further assistance.

Galliprant Reviews

Galliprant is perceived well in the veterinary community as an effective medication for many dogs living with arthritis. I have personally prescribed Galliprant to many of my patients with good results. I like that it has less risk for side effects compared to other brands of NSAIDs currently available. Only having to give Galliprant once a day is also a great perk for many pet parents, especially if their dogs do not readily take medications. The downside to Galliprant is that it is quite expensive for large breed dogs.

Dogs who would benefit from Galliprant include those with arthritis who need an alternative to traditional NSAIDs, such as Rimadyl or Metacam, because of underlying health conditions like liver and kidney diseases. While a medication called gabapentin can also be used for pain relief in dogs, it is generally more effective for pain and inflammation of the spine, brain, and nervous system rather than the joints. It is also commonly prescribed to prevent seizures. For dogs experiencing arthritis, an NSAID is a better choice. Your pet’s veterinarian can recommend the best type of NSAID for your dog based on their particular needs and health history.

Galliprant Side Effects

When giving Galliprant to your dog, you should watch for potential side effects that can occur, which include the following:

Vomiting
Diarrhea
Reduced appetite
Soft stool containing mucus or blood

While less common, some dogs may experience decreased energy and tiredness while taking this medication. If you notice any of these side effects or other abnormal behaviors while your dog is taking Galliprant, promptly contact your pet’s veterinarian for guidance.

Galliprant should not be taken with aspirin, any other types of NSAIDs, or corticosteroids. Giving these together can result in an increased risk for serious side effects, including ulcers of the stomach or intestines and loss of appetite. Be sure to let your pet’s veterinarian know about any medications and supplements your dog is taking prior to starting them on Galliprant.

Galliprant Dosage for Dogs

The dosage of Galliprant will vary based on your dog’s weight. It is important to note that dogs should be at least 9 months of age and should weigh at least 8 pounds for safe and accurate dosing of this medication [2]. Galliprant is available in 20mg, 60mg, and 100mg tablets. Your dog’s veterinarian will determine the proper dosage and will monitor their response while they are taking the medication.

What Does Galliprant Cost?

The cost of Galliprant will vary based on your dog’s size and your location. Pet parents can expect to spend about $40-$50 per month for smaller dogs, while costs can increase to around $100 a month for large breed dogs.